Dixon sequence imp in contrast-enhanced phase

A 57-year-old female patient with breast biopsy sections who underwent a mammogram for high-risk screening

Image: A. The axial T1-weighted fat-unsaturated MR image shows no region of the signal space. No reader detected a clip using this sequence. The contrast-enhanced Dixon image shows a signal void in the right breast (arrow), which corresponds to the MammoMark/CorMark Bread Tie biopsy section. The three readers detected a syllable in this sequence, with confidence scores of 4, 3, and 2; All evaluations are rated as true positive (ie, detected with confidence score ≥2).
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Credit: ARRS/AJR

Leesburg, Virginia, September 14, 2022According to ARRS American Journal of Oncology (AJR)enhanced in-phase Dixon sequencing could reduce the need for correlation between other imaging modalities to better identify areas of prior biopsy during breast MRI interpretation.

Compared with clinical sequences, phase contrast-enhanced Dixon had higher sensitivity for detection of breast biopsy sections on MRI, as well as higher reader confidence and contrast-to-noise ratio (CNR), without change in positive predictive value (PPV),” the corresponding author wrote. and the first participant, Michael W Taylor ChuMD, master of public health, from Duke University Medical Center in Durham, North Carolina.

Dr. Taylor Chu and team’s retrospective study numbered 164 women (mean age, 50.3 years) with a total of 281 breast biopsy sections who underwent contrast-enhanced breast MRI between January 2, 2019 and April 16, 2020. Sequence information, biopsy section details In this study, three radiologists independently commented on their findings for three clinical sequences—T1-weighted (T1W) non-fat-suppressed (NFS), STIR, and phase I lipid-suppressed T1W dynamic contrast (FS)—plus Dixon in Enhanced phase contrast. Then confidence was scored on a scale of 1-4.

Finally, compared to T1W NSF, STIR, and T1WFS sequences, phase contrast-enhanced Dixon sequencing showed the highest sensitivity for breast biopsy section detection (85.1% vs. 26.6%–78.2%), highest reader confidence (3.5 vs. 1.7–3.0), and highest rate A refined rate (4.05 vs. 0.54–1.21), with no significant difference in PPV (96.4% vs. 92.2%-96.1%).

The use of Dixon sequencing in contrast-enhanced phase may “help address the current challenge of interpretation of routine clinical breast MRI”, the authors of this AJR Conclude the article.


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